IF you have 5 symptoms you are in depression circle - Depression a cause of 264 million suicides worldwide.

In  2013, an American actor, voice actor and a comedian die because of depression. YEAH, comedian and his name was robin Williams. Depression not judge by physical act because it kill inside your whole body, personality and yourself biologically.

                             

What is REAL depression according to research?

According to different researches, the capturing point for depression is, it is the feeling of sadness and disappointment, person not showing interest in its previously favorite activities and persons. As estimated worldwide, around 264 millions peoples die just cause of depression. No one take it or accept it as serious medical illness, but it is true, it cause serious co-morbidity conditions like cardiovascular diseases , diabetics etc.

Factors that catalyze depressions?

Most of the factors catalyze or enhance depressive mood which include social stress, complex social interaction among psychological and biological factors . LOSS OF EMPLOYMENT and CHILDHOOD ADVERSITY are important factors of depression.

GENETICS : are also play role in depression, from parents depression can gifted to children in genetics, for example as in the case of identical twins if one baby inherited depression 70% chances of depression also possible in second baby.

BIOCHEMISTRY: Due to the unbalancing or loss of some important chemicals in brain i.e nor epinephrine, serotonin and dopamine.

ENVIRONMENTAL FACTOR: It also become the major cause of depression nowadays , due to continuous pressure and exposure of ignorance, failure, poverty and violence .

PERSONALITY : Personality can be build-up from family or society, friends . Peoples with low esteem personality can easily overwhelmed by depression.

How can you analyze depression in common person?

It is MYTH hat depression can only affects elderly peoples, every person have equal chances of depression regardless of any age group. Sometimes peoples with depression didn’t face any major symptoms that can be traceable, but with major depressive disorder following symptoms are associated that include,

       1. Psychomotor agitation , retardation and restlessness.
 2. Lack of activity in patient’s affect or emotional expression

Ok !! lets have a simplified look of these two above symptoms:

• 1.       Loss of appetite or weight loss
• 2.       Lack of interest or demotivated from all activates and work.
• 3.       Insomnia or hypersomnia , sleep pattern disturbed.
• 4.       Fatigue or laziness
• 5.       Feeling or worthlessness
• 6.       Depressed mood that can be evaluated as irritable mood in adults  and childrens
• 7.       Lack of concentration in almost activities.

According to THE DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDER (DSM-5), 5 symptoms should be present in patient in which one must be second symptom, more than 2 weeks .

Relationship of receptor neurotransmitter – cause of depression:

In limbic system, prefrontal cortex, amygdala and hippocampus, unbalance of receptor- neurotransmitter relationship will lead to depression. As we know our brain have certain neurotransmitter which play important role in our daily routine work .decreases levels of  norepinephrine and serotonin result in lethargy and irritability respectively.

But what about suicidal thoughts !!

Decrease levels of serotonin will initiate suicidal cycle or thought and feeling of worthlessness .

How there is UNBALANCING in neurotransmitter levels?

Naturally our body produce some neurotransmitter that can release and absorb by neuron after performing its action it can destroy ( in this case its metabolize by monoamine oxidase) or it can reuptake (selective serotonin reuptake inhibitor and serotonin norepinephrine reuptake inhibitor) / stored until needed. Due to impaired synthesis , increase metabolism and uptake, neurotransmitter are unavailable at the time of need. That will lead  to unbalancing of neuerotransmitter and major depressive disorder.

BARRIER IN PREVENTION:

Most of peoples think it is not treatable or it is not a mental illness that’s why suicidal attempts are increase in different countries , also in developed countries world wide.

Its have proper screening and treatments and how to control it naturally through meditation and exercise ,discuss in next blog.